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The two main types of oesophageal, or food pipe cancer, display distinct genetic characteristics and should be studied separately in clinical trials, according to a large US study. The analysis from The Cancer Genome Atlas (TCGA) Research Network calls into question the classification of the disease. Experts believe the study could have implications for the design of future clinical studies, serving as a “reference manual” for those running clinical trials and developing new drugs, said lead researcher Dr Adam Bass from the Dana-Farber Cancer Institute in the US. Tumours are commonly classified based on how the cancer cells look under the microscope and where the cases occur in the world.

See original article at: https://www.cancerresearchuk.org/about-us/cancer-news/news-report/2017-01-05-large-genetic-analysis-of-oesophageal-cancer-could-lead-to-better-clinical-trials