Cutting cancer diagnosis delays means understanding each patient’s journey

Anne Li The National Cancer Diagnosis Audit (NCDA) found that more than 7 in 10 cancer patients first reported symptoms at the GP surgery, or during a GP home visit. Less than 1 in 10 first presented at A&E. The good news is that many patients who were first seen…...

Read more

News digest – health warning on cigarettes, nanoparticles, ‘heat-not-burn’ tobacco and…. artificial intelligence?

Anne Li This week, Cancer Research UK gives us updates on cigarettes, treatment for advanced breast cancer, obesity, lymphoma, nanoparticles, drugs for stopping alcohol consumption, ‘Heat-not-burn’ tobacco products, and finally…. artificial intelligence? See original article at: https://scienceblog.cancerresearchuk.org/2017/12/16/news-digest-health-warning-on-cigarettes-nanoparticles-heat-not-burn-tobacco-and-artificial-intelligence/...

Read more

Science Surgery: ‘Does having had cancer make you more likely to develop it again?’

Anne Li Tommy asked Cancer Research UK: “Does having had one type of cancer (and cured) make you more susceptible to getting any other type?” To begin answering this question, you have to know the difference between second cancers, which this relates to, and secondary cancers. Second cancers are those…...

Read more

Cancer Research UK announces drug discovery collaboration with Celgene Corporation

Anne Li Cancer Research UK announced on Friday, December 15th, the signing of a five-year drug-discovery collaboration between its subsidiary, Cancer Research Technology (CRT), and Celgene Corporation, to discover, develop and commercialise new anti-cancer treatments. This arrangement represents an expansion of Cancer Research Technology’s theme-based translational model that now encompasses…...

Read more

Immune cell therapy results are ‘landmark moment’ in lymphoma treatment

Anne Li Four in 10 patients with aggressive lymphoma were cancer-free 15 months after treatment with engineered immune cells, according to new US clinical trial results. The study involved 108 patients with large B cell lymphoma who didn’t respond to standard treatment. Around 6 in 10 patients were alive 15…...

Read more

Health warnings on cigarettes could deter young people

Anne Li Young people are less likely to try cigarettes with the printed health warning ‘Smoking kills’ on each stick than standard cigarettes, according to a new study by Cancer Research UK published in Nicotine & Tobacco Research. Researchers wanted to examine new, innovative ways to reinforce health messages around…...

Read more

New technique could reveal immunotherapy targets, study finds

Anne Li Researchers at the Stanford University School of Medicine and their colleagues have developed a way to pinpoint potential targets for cancer therapies that rely on the body’s immune system. Those targets are molecules called antigens, which appear on the surface of tumor cells and other malignant or damaged…...

Read more

Hunting for immune cells’ cancer targets

Anne Li By screening millions of molecular targets, researchers have uncovered a tumor beacon detected by the immune cells of two patients with colorectal cancer. The screening technology, developed by Howard Hughes Medical Institute Investigator (HHMI) Christopher Garcia and colleagues after almost 20 years of basic molecular studies of the…...

Read more

A kiss of death for prostate cancer

Anne Li Hokkaido University researchers have uncovered a cellular protein that stabilizes a tumor promoting signaling pathway, suggesting a new target to treat prostate cancer. The drug Gefitinib is used to treat breast, lung, and other cancers by inhibiting epidermal growth factor receptor (EGFR) signaling, but it has only a…...

Read more

Cancer overrides the circadian clock to survive

Anne Li Tumor cells use the unfolded protein response to alter circadian rhythm, which contributes to more tumor growth, researchers find. A key part of the the circadian clock opposes this process. For tumors to grow and spread, cancer cells must make larger than normal amounts of nucleic acids and…...

Read more