Anne Li Our body has an internal biological or “circadian” clock, which cycles daily and is synchronized with solar time. New research done in mice suggests that it can help suppress cancer. The study, publishing 7 December in the open access journal PLOS Biology by Dr Angela Relógio from the…...
First line combination therapy improves progression-free survival in advanced lung cancer
Anne Li A new combination therapy for the first line treatment of advanced non-squamous non-small-cell lung cancer (NSCLC) improves progression-free survival (PFS), according to results of the phase III IMpower150 trial presented at the ESMO Immuno Oncology Congress 2017. “This is the first phase III trial to report on the…...
Mechanism identified behind enzyme involved in liver and other human cancers
Anne Li To understand what has gone wrong when cancer occurs and to create new possibilities for treatment, it is important to understand the molecular mechanisms behind what is happening at the cellular level. New research, which is now published in the journal Molecular Cell, explains how the motor of…...
Molecular beacon signals low oxygen with ultrasound
Anne Li Areas of hypoxia, or low oxygen in tissue, are hallmarks of fast-growing cancers and of blockages or narrowing in blood vessels, such as stroke or peripheral artery disease. Researchers have developed a way to find hypoxic spots noninvasively in real time. The researchers developed an oxygen-sensitive molecular beacon…...
Cold discomfort: Increasing cancer rates and adaptation of living in extreme environments
Anne Li It is well known that cancer incidence is increasing worldwide, with pockets of human populations and geographical locations seemingly at higher risk than others. Researcher Konstantinos Voskarides, Ph.D., of the Univesity of Cyrpus’ Medical School, noted that populations living in very low temperatures, like in Denmark and Norway,…...
Anti-aging protein could be targeted to rejuvenate immune cells
Anne Li An anti-aging protein called SIRT1, commonly known for being activated by red wine, has been shown to protect against age-related diseases, such as cancer, neurodegeneration, and cardiovascular disease. A study now reveals that it could also be targeted to rejuvenate cells in the immune system. The protein in…...
Cancer drug leads to ‘drastic decrease’ in HIV infection in lung cancer patient
Anne Li The first evidence that a cancer drug may be able to eradicate HIV-infected cells in humans has now been revealed by researchers. They report that while treating an HIV-infected lung cancer patient with the cancer drug nivolumab, they observed a ‘drastic and persistent decrease’ in the reservoirs of…...
